KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG9
All Species:
30.3
Human Site:
S254
Identified Species:
60.61
UniProt:
Q9H0W8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0W8
NP_061981.2
520
57651
S254
E
R
G
G
N
Q
T
S
G
I
D
F
F
I
T
Chimpanzee
Pan troglodytes
XP_001158051
495
54769
E247
A
Q
S
A
E
M
K
E
R
G
G
N
Q
T
S
Rhesus Macaque
Macaca mulatta
XP_001106959
520
57618
S254
E
R
G
G
N
Q
T
S
G
I
D
F
F
I
T
Dog
Lupus familis
XP_533650
520
57589
S254
E
R
G
G
N
Q
T
S
G
I
D
F
F
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB90
520
57602
S254
E
R
G
G
N
Q
T
S
G
I
D
F
F
I
T
Rat
Rattus norvegicus
Q5PQS6
520
57614
S254
E
R
G
G
N
Q
T
S
G
I
D
F
F
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515769
130
14079
Chicken
Gallus gallus
Frog
Xenopus laevis
Q05AW9
508
56581
S243
E
R
A
G
N
Q
T
S
G
I
D
F
F
I
S
Zebra Danio
Brachydanio rerio
XP_001923815
503
56076
S241
E
R
A
G
N
Q
S
S
G
I
D
F
Y
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395241
359
40784
G116
F
L
V
V
G
C
L
G
A
Q
G
V
G
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780386
532
57732
S266
E
Q
A
L
H
Q
T
S
G
M
E
M
F
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001143814
423
45897
M180
P
S
V
L
I
D
M
M
R
P
D
G
S
S
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
99.2
98.2
N.A.
97.3
96.9
N.A.
21.9
N.A.
74.8
72.6
N.A.
N.A.
29.4
N.A.
37.4
Protein Similarity:
100
95.1
99.6
98.6
N.A.
98.4
98.4
N.A.
22.5
N.A.
85.5
85.3
N.A.
N.A.
44.8
N.A.
53.2
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
0
N.A.
86.6
80
N.A.
N.A.
0
N.A.
53.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
0
N.A.
93.3
93.3
N.A.
N.A.
6.6
N.A.
80
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
39.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
25
9
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
67
0
0
0
0
% D
% Glu:
67
0
0
0
9
0
0
9
0
0
9
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
59
59
0
0
% F
% Gly:
0
0
42
59
9
0
0
9
67
9
17
9
9
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
59
0
0
0
67
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% K
% Leu:
0
9
0
17
0
0
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
9
9
0
9
0
9
0
0
0
% M
% Asn:
0
0
0
0
59
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
17
0
0
0
67
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
59
0
0
0
0
0
0
17
0
0
0
0
0
0
% R
% Ser:
0
9
9
0
0
0
9
67
0
0
0
0
9
9
25
% S
% Thr:
0
0
0
0
0
0
59
0
0
0
0
0
0
9
67
% T
% Val:
0
0
17
9
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _